Mikro Biyosistemler

TurkeyProfile 82%

We develop a microfluidic liquid biopsy platform for circulating tumor cell isolation and enumeration from blood samples of cancer patients with competitive edge on performance and cost.

Problem

CTCs are very rare cells (as low as 1 in billions of other blood cells), bringing significant challenge in their efficient detection and isolation.

Solution

MikroBiyo’s tagCTC tackles this challenge with its unique 3-stage cascade microfluidic approach that performs two consecutive filtering followed by electrical cell counting: (1) hydrodynamic enrichment via size/deformability-based differences; (2) immunoaffinity-based cell capture by antibody-based immobilization; and (3) electronic enumeration based on impedance spectroscopy (IS) technique, in a single lab-on-a-chip platform.

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